Silicon Valley venture firm Andreessen Horowitz on Friday announced $15 billion in new funds, its largest fundraising haul to date, with the firm promising to back startups in AI, crypto and beyond that it says advance American interests.
The new funds include $6.75 billion for its growth fund. It also raised $1.176 billion for its American Dynamism practice, which backs defense and security related startups; $1.7 billion for its Apps fund, $1.7 billion for its Infrastructure fund; $700 million for its Bio & Health fund; and $3 billion for what it calls “other venture strategies.”
The fundraising kick comes on the back of the strongest year for North American startup investment in four years. Startups based in the region raised $280 billion in 2025, per Crunchbase data, up 46% year over year. The majority of venture dollars invested in North America last year went to the AI sector.
Andreessen Horowitz, also known as a16z, was a major driver of that investment surge. Though the firm invests mostly in the U.S., it was the second most active post-seed venture investor globally last year, per Crunchbase data, behind only startup accelerator Y Combinator.
All told, a16z participated in at least 165 post-seed startup funding deals in 2025, including investments in Cursor maker Anysphere, legal tech unicorn Harvey, predictions market Kalshi, AI lab Safe Superintelligence, publishing platform Substack, surveillance startup Flock Safety, AI voice startup ElevenLabs, and Databricks.
The Menlo Park-based firm claims to have raised 18% of all venture capital dollars invested in the U.S. in 2025. Its new fundraising kick comes on the heels of the slowest year for new fundraising by venture capital firms since 2017, per preliminary data from the National Venture Capital Association and Pitchbook.
In a blog post, firm co-founder and General Partner Ben Horowitz highlighted the firm’s focus on investing domestically, as well as themes around American national security and the imperative for the U.S. to maintain a technological lead over rivals like China.
“Our mission is ensuring that America wins the next 100 years of technology,” he wrote. “That starts with winning the key architectures of the future – AI and crypto. It continues with applying those technologies to the key areas that generate human flourishing: biology, health, defense, public safety, education, and entertainment. And it culminates with the American government adopting these technologies to defend and advance American interests.”
The firm’s notable exits over the years include Airbnb, Coinbase, Lyft, Pinterest, Slack and Okta.
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Illustration: Dom Guzman
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