Verdict
The Keychron M5 is a capable wireless gaming mouse with the pleasant touch of a vertical one. It’s got a powerful sensor and polling rate combo inside for snappy movement, alongside good battery life and convenient, lightweight software. It is also rather comfortable, although the shape can make it a more unwieldy option in fast-paced games.
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Immensely powerful internals -
Comfortable shape -
Solid battery life
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Vertical shape is a little unwieldy for serious gaming -
Some may prefer something a little more stylish
Key Features
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Vertical shape
The M5 is a more ergonomically-minded mouse with a vertical shape to bring your hand to a more natural position. -
30,000 DPI sensor and 8000Hz polling
It also packs the innards of a seriously potent gaming mouse with high sensitivity and polling rate. -
Up to 140 hours battery life
Keychron also rates the M5 to have some good battery life, lasting for several weeks on a charge.
Introduction
The phrase ‘ergonomic gaming mouse’ almost made me spit out my tea when I heard it, as it isn’t a product type I thought would see the light of day – enter the Keychron M5 to prove me wrong.
Coming from the same folks behind excellent options in the past, such as the M3 Mini (Metal Edition) and the M6, it represents quite a unique proposition in that it’s a vertical mouse for better wrist position that comes jam-packed with features traditionally meant for powerful gaming options such as a 30,000 DPI sensor and an 8000Hz polling rate, plus up to 140 hours of battery life and versatile wireless connectivity.
In theory, this would make the M5 quite an expensive option, but in keeping with Keychron’s reputation for serious value for money, it’s £69.99/$69.99. That’s half the price of some of the best gaming mice we’ve tested, including the Razer DeathAdder V4 Pro and Logitech G Pro X Superlight 2 Dex, although whether it’s designed to compete with those is a different story.
I’ve been testing the M5 to see if it’s too good to be true, or if it’s a genuinely excellent contender.
Design
- Vertical chassis for optimal comfort
- Lighter plastic shell
- Pleasant button arrangement
The most noticeable thing about the M5 is its vertical shape that sets it apart from more standard form factor mice. It’s designed to raise your hand up to a more natural position to reduce the chance or impact of repetitive strain injuries that can come from awkwardly using a standard mouse.
In the case of this Keychron mouse, it puts it at a 47-degree angle in a position that’s commonly referred to as the ‘handshake’ position for obvious reasons. This is commonplace among lots of other vertical ergonomic mice, while at 95g, this option is also considerably lighter than the competition.
This, combined with the somewhat textured plastic shell, makes the M5 an immensely comfortable mouse to use. As someone who is getting some wrist pain at the moment, I can certainly see the appeal. Being wider at the base also provides more stability, keeping it in the right position.
With a white plastic chassis bereft of any texturing or theming, it’s easy to pass off this Keychron mouse as quite basic. For the kind of mouse this is and the price of it though, it’s perfectly fine in my eyes. As well as white, is available in black if you wish.
As for buttons, there are five across the mouse, with two main ones and a scroll wheel on the right side, plus two navigation buttons on the left. You’ll also find a rubberised scroll wheel above the navigation buttons in a similar vein to the Logitech MX Master 3S I traditionally use every day.
On the underside of the M5 are a handful of further buttons – one for changing DPI, one for changing polling rate, and another for choosing between its three channels of wireless connectivity. There is also a toggle switch for turning the mouse on and off, and into either Bluetooth or 2.4GHz modes.
Performance
- Potent 30,000 DPI sensor
- 8000Hz polling rate is a pleasant touch
- Solid battery life and connectivity
It’s inside where things get especially interesting for the M5. As opposed to bundling it with a productivity-focused 4000 or even 8000 DPI sensor, they’ve put in a powerful PixArt 3950 with up to 30,000 DPI of sensitivity.
In practice, nobody is necessarily going to use that much, as it makes any mouse too sensitive to use in any real scenario. But if you want immensely responsive inputs, then it goes a long way to helping that.
As with the Lemokey G1, the M5 is part of an exclusive club of 8000Hz polling rate mice. This essentially means it reports inputs to host devices, such as a gaming PC, much more often than more ‘standard’ mice do with a 1000Hz rate. It results in more accurate and responsive inputs that seasoned players are likely to feel more so than us casual folk.
With both of these things in kind, I took the M5 into some rounds of Counter Strike 2 – my usual testing ground for gaming mice. I was almost surprised at how responsive this vertical mouse felt given the sensitivity and polling rate advantage, and how accurate it was.
However, the fact that it’s a little heavier and taller than more usual flat mice means it isn’t as flickable or nimble in fast situations. This isn’t an issue with the M5’s internals per se, but just a consequence of its form factor.
With this in mind, I didn’t have the same issue in general work use, with the vertical form factor, accurate sensor, and snappy Huano switches inside making for a comfortable and responsive feel.
The M5’s wireless connectivity is convenient, with both 2.4GHz and Bluetooth methods working virtually plug-and-play over either my Windows gaming PC or my MacBook Pro. I had no issues on either device.
Keychron rates this vertical mouse to last for up to 140 hours on a charge, although that is with the caveat of working over Bluetooth. Go to the 2.4GHz receiver and with 1000Hz polling, and you’ll get 120 hours. At 8000Hz, this drops off to just 40 hours, which is quite normal as it’s quite an intensive battery drain in spite of the sensor’s efficiency.
Software and Lighting
- Lightweight, web-based software
- No RGB lighting to speak of
Software duties for this Keychron mouse are handled by the brand’s lightweight, web-based Launcher software that negates the need for any downloaded software solution.
It provides a slick and convenient means for mapping buttons, changing DPI level, recording macros and more advanced settings such as switch debounce times and lift-off distance across five profiles. While you may not get other features such as DPI matching and changing DPI levels on both an X and Y axis, as found on the competition, what’s here is more than perfectly usable.
One area where you won’t find the M5 impressive is with its RGB lighting, and that’s simply because it doesn’t have any. This has become more common among performance-first ultralight gaming mice in the more standard form factor, and isn’t too much of a sore miss here.
Should you buy it?
You want a powerful vertical mouse
Not many other vertical mice have the potency of the Keychron M5, and if that’s important, then this is a marvellous choice.
You want an optimal gaming option
The vertical shape isn’t the best for out-and-out gaming though, as it can feel a little unwieldy against more standard mice of a similar power level.
Final Thoughts
The Keychron M5 is a capable wireless gaming mouse with the pleasant touch of a vertical one. It’s got a powerful sensor and polling rate combo inside for snappy movement, alongside good battery life and convenient, lightweight software. It is also rather comfortable, although the shape can make it a more unwieldy option in fast-paced games.
For more general work, though, it’s a top contender that’s comparably priced against the Logitech Lift, but provides a lighter chassis and lots more oomph if you need it. For more typical gaming workloads, I’d wager you’re better off with the Lemokey G1 that comes with the same sensor and polling rate combo at a similar price tag.
With this in mind, the Keychron M5 is still a fantastic and quite unique ergonomic option. For more options, check out our list of the best gaming mice we’ve tested.
How We Test
We use every mouse we test for at least a week. During that time, we’ll check it for ease of use and put it through its paces by playing a variety of different genres, including FPS, strategy and MOBAs.
We also check each mouse’s software to see how easy it is to customise and set up.
- Used as a main mouse for over a week
- Tested performance in a variety of games
FAQs
The Keychron M5 weighs 95g, making it heavy for a gaming mouse, but quite light for a vertical one.
Full Specs
Keychron M5 Review | |
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UK RRP | £69.99 |
USA RRP | $69.99 |
Manufacturer | – |
Size (Dimensions) | 59 x 117 x 72 MM |
Weight | 95 G |
Release Date | 2025 |
First Reviewed Date | 13/08/2025 |
Connectivity | 2.4GHz, Bluetooth, USB-C |
Cable Length | 1.8 Meter |
Battery Length | 140 hrs |
DPI range | 100 30000 |
Number of Buttons | 5 |