Want to keep track of the largest startup funding deals in 2025 with our curated list of $100 million-plus venture deals to U.S.-based companies? Check out The Crunchbase Megadeals Board.
This is a weekly feature that runs down the week’s top 10 announced funding rounds in the U.S. Check out last week’s biggest funding deal roundup here.
This week featured a lot of funding deals with a lot of zeroes on the end. Generative AI powerhouse Anthropic, of course, boasted the most zeroes with its $30 billion Series G, the second-largest venture funding round of all time. Other big fundraisers included robotics startup Apptronik, fusion innovator Inertia Enterprises, and space tech unicorn Axiom Space.
1. Anthropic, $30B, Generative AI: Anthropic raised $30 billion in a massive Series G funding round that values the San Francisco-based generative AI company at $380 billion post-money. The financing marks the largest venture funding deal of 2026 so far and the second-largest of all time, per Crunchbase data. GIC and Coatue led the raise, which was also “co-led” by D.E. Shaw & Co. Ventures, Dragoneer Investment Group, Founders Fund, Iconiq Capital and MGX, according to the company.
2. Apptronik, $520M, humanoid robots: AI-powered robotics company Apptronik added $520 million in new financing in an extension of its $415 million Series A raise in February 2025, The investment brings the total round to over $935 million for the Austin-based company.
3. Inertia Enterprises, $450M, fusion energy: Livermore, California-based fusion power startup Inertia Enterprises announced that it secured $450 million in Series A funding. Bessemer Venture Partners led the round for the 2-year-old company, joined by Google Ventures, Threshold and other backers.
4. Axiom Space, $350M, space tech: Axiom Space, a startup that is building a successor to the International Space Station and developing spacesuits for a moon mission, closed on $350 million in new financing. Type One Ventures and Qatar Investment Authority led the round for the Houston-based company.
5. Runway, $315M, AI: Runway, an AI research and technology startup, picked up $315 million in a Series E round. General Atlantic led the financing, which set a $5.3 billion valuation for the New York-based company, up from $3.3 billion last April.
6. Talkiatry, $210M, mental health: Talkiatry, a provider of in-network psychiatry services to health systems and employers, picked up $210 million in Series D funding, led by Perceptive Advisors. The round brings total funding to date for the New York-based company to more than $400 million.
7. Solace Health, $130M, healthcare: Redwood City, California-based Solace Health, a digital platform that connects patients with expert healthcare advocates, raised $130 million in Series C funding. IVP led the financing, which set a valuation of over $1 billion for the 4-year-old company.
8. Garner Health, $118M, healthcare: Garner Health, a digital platform that helps patients find healthcare providers, raised $118 million in Series D financing. Kleiner Perkins led the round for the New York-based company.
9. (tied) Simile, $100M, AI simulation: Palo Alto, California-based Simile, a startup focused on applying AI to create simulated environments and simulation tools with AI agents, raised $100 million in Series A funding led by Index Ventures.
9. (tied) Loyal, $100M, dog longevity: Loyal, a startup focused on drugs to extend healthy lifespans in senior dogs, raised $100 million in Series C funding that it says will provide the capital required to move from late-stage development to market readiness. Venture fund Age1 led the financing for the 7-year-old, San Francisco-based company.
Methodology
We tracked the largest announced rounds in the Crunchbase database that were raised by U.S.-based companies for the period of Feb. 7-13. Although most announced rounds are represented in the database, there could be a small time lag as some rounds are reported late in the week.
Illustration: Dom Guzman
Stay up to date with recent funding rounds, acquisitions, and more with the
Crunchbase Daily.
